Epilepsy, also known as seizure disorder, is one of the world’s most common and most serious neurological conditions, afflicting about 50 million people around the globe. It’s estimated that about 70 percent of the world’s epilepsy patients can control their seizures by using the two dozen or so anticonvulsant drugs that are on the market. As long as they take their daily pills, they’re essentially seizure-free. But some 30 percent of epilepsy patients are considered “refractory” to currently marketed medications. That is, those patients are unable to achieve adequate seizure control using existing drugs, or combinations of existing drugs. It’s that smaller number of patients on which St. Louis startup company Tansna Therapeutics is focusing. From laboratory facilities within the Cortex business incubator complex in mid-town St. Louis, Tansna’s team is refining experiments that were launched four years ago at the University of Iowa by the company’s co-founder Max Baker, an anesthesia researcher with a PhD in Pharmacology and a strong focus on medicinal chemistry. “Max is very interested in anesthesia drugs like propofol, which are commonly used to put you to sleep when you’re having surgery,” says George Capps, the director of business development for Tansna. Hear George Capps, the director of business development for Tansna, on KMOX Radio Tuesday, October 6 at 10:50am central Baker was trying to build a better propofol – by making chemical modifications to the well-known drug that would preserve its anticonvulsant activity and reduce its sedative effects. “Propofol”, says Capps, “is known to have very powerful anticonvulsant properties, and in fact it’s frequently used in emergency rooms for patients who are experiencing uncontrolled seizures. These are patients with difficult-to-treat seizures who could...Read More
Do you have a great idea you think might be a money maker, but you’re not sure where to turn to find out if your hunch is a good one? A St. Louis entrepreneur says he can provide you some direction, starting next month, via a new online video program called “Cash or Crash.” Entrepreneur Dr. Renato Cataldo has already founded one video-based company in St. Louis. His CrazyForEducation.com start-up collects instructional videos from teachers and distributes them to students and parents for a fee, with the teachers who create the videos sharing in the revenue. Hear founder Renato Cataldo’s interview on KMOX Radio from Tuesday, 9/22 Now Cataldo is turning his attention to those who have a concept, but no forum to find out if their idea’s worth pursuing. He says his aim is to reach “the average person, from service worker to professional. The projects we’ll review may not be the next $100 million business, but they’ll be just as important to the individuals who share their stories and their passion.” Here’s how it will work: the person behind the idea will fill out an online form at CashOrCrash.com, and, if selected to continue on to the next phase, will take part in a pre-interview with Cataldo. “We’re looking for people who are still at the idea stage. We’re not interested in people who have already started their business, or are farther down the road,” he says. “The other thing we’re looking for is people who can improve their lives through their ideas — the people who would go from being a $10 an hour person to one who can make $50,000 a year with their idea,...Read More
Madison County, Illinois has turned to a St. Louis startup company to help guide the county’s future investment decisions. The southern Illinois county’s selection of PFITR (pronounced P-fitter) comes several months after County Treasurer Kurt Prenzler announced Madison County received a $340,000 settlement of an arbitration claim against an Arkansas securities firm that was charging excessive commissions on county investments made prior to Prenzler’s administration. The firm settled the 2011 claim without admitting liability. Prenzler says the selection of PFITR, a Software as a Service (SaaS) designed to give public treasurers, chief financial officers and finance committee members the data they need to make better decisions about investing the tax money citizens provide to local governments, “gives us another tool in our toolbox that we can use to make sure we’re on solid ground,” in terms of its investments. Madison County will pay $21,000 annually for the service. PFITR CEO Jim Koetting says PFITR is designed to give public fund managers real-time financial data and analysis, allowing them to better evaluate upcoming risks, and make better investment decisions. Click to hear PFITR CEO Jim Koetting and Madison County Treasurer Kurt Prenzler on KMOX Radio Koetting says PFITR’s Bond Price Validation Tool will help guide the county in what can be a tricky area for public fund investors – bond investing — since some brokers embed the price of their commissions inside the price they quote for the cost of a bond. “Before the advent of our software,” says Koetting, “a treasurer had very few options of checking true market value and getting an idea of what the broker is charging for a commission because that cost was marked in the...Read More
Something big is happening in St. Louis.
If you’re plugged into the local innovative entrepreneurism movement, you know we’re becoming one of the fastest growing centers of biotech, IT and consumer entrepreneurship in the nation.
Here’s what St. Louis entrepreneurs are saying about the opportunities and outreach created for them by InnoVox STL:
|“The owner of a chain of grocery stores in Southern Illinois heard me on your interview. About two weeks later he was meeting with the regional head of RDS (with whom I’ve formed a business relationship) and mentioned he heard us on the radio and wanted to know what RDS thought of our system. I set up a meeting and made a demonstration and he agreed to install DealieDo in his stores. We are getting the installation ready now. All because of one 7-minute interview that you coordinated!!! Thank you!!!!” – Rob Rose, Dealido
“Before I returned to the office we received an inquiry directly from the KMOX spot – that was awesome! We have not closed the deal but we are getting closer. Had several more calls related to the spot over the last couple of months.” – Tim McIntyre, eTwist.
“Immediately following our appearance on KMOX Radio, we had dozens of e-mails and SMS messages congratulating us. One of those messages came from a very large event production company in St. Louis who wanted to engage us. Through a series of additional efforts, we are now in a long term contract with that company. So, directly springing from our participation/exposure, we were invited to work with this company and are now growing that relationship.” — Brian Slawin, BusyEvent
“We received several inbound leads thanks to the KMOX Radio appearance from InnoVox. RoverTown was able to present to the St. Louis Cardinals thanks to the InnoVox Connect pitch event. We were able to meet the Cardinals’ staff and now are proud to call the Cardinals one of RoverTown’s clients. Additionally, we were invited to attend 2014 St. Louis Arts Awards event thanks to InnoVox Connect. We were able to meet Dave Steward of World Wide Technologies from the event and have built a relationship with him.” – Jeffry Harrison, Rovertown
“A local investor we had been talking to for about 5-months happened to hear the KMOX appearance live and sent me a note saying I sounded good and we should re-connect sometime soon. He is now an investor in our company, the positive PR he happened to stumble upon let him know we were still hear and going strong, which led to him re-engaging.” — Tom Cohen, Nanopore
“In the weeks prior to my appearance on the KMOX , my website was averaging roughly 20 sessions a day. On the day of appearance, it spiked to 209 sessions. This spike resulted in 6 transactions (tickets sold) on our website. Also, as a result of the KMOX appearance, I received another marketing opportunity to be on Fox2news (directly attributable to the KMOX appearance). – Pete Manzo, EAT STL
“After the radio interview, I received an email from someone at National Information Solutions Cooperative about a potential partnership. Without the radio interview, NISC would not have initiated the conversation that soon. Also, several people signed up for our newsletter in the days following the KMOX interview and Business Journal article.” –Ty Benefiel, Metergenius
“Lumate and I have definitely benefited from the InnoVox Connect event with a local arts organization. Many connections to leaders in organizations from the St. Louis area have developed out of this event and have helped me further my network of connections.” – Quentin Ortega, Lumate
“The exposure we received from KMOX/ STL Biz Journal was vital in helping us to establish our name and business recognition in the greater STL area. Your piece greatly aided our recruiting efforts as many job candidates reached out to us after hearing the KMOX piece.” – Trip Goodloe, GirlsAskGuys